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Antide (CAS 112568-12-4) Product Details Antide, with CAS Number 112568-12-4, is a potent synthetic GnRH (Gonadotropin-Releasing Hormone) antagonist, also known as Antide Acetate. It is a linear modified peptide with N-terminal acetylation and C-terminal amidation, which significantly enhances its ...
GMP factory supply high purity Antide peptide CAS 112568-12-4 Antide powder for research
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Product Basic Information
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Item
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Details
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CAS Number
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112568-12-4
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Product Name
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Antide; Antide Acetate; GnRH Antagonist
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Chemical Formula
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C₈₂H₁₀₈ClN₁₇O₁₄
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Molecular Weight
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Approx. 1591.29
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Appearance
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White to Off-White Solid Powder
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Purity
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≥98% (HPLC); ≥99% available for research grade
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Solubility
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Approx. 10 mg/mL in Water (ultrasonic assistance recommended); Soluble in appropriate organic solvents
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Storage Condition
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Sealed, Protected from Light; -80°C for 2 years, -20°C for 1 year (powder); -80°C for 6 months, -20°C for 1 month (dissolved); Avoid repeated freeze-thaw cycles
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Shelf Life
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24 Months under Proper Storage Conditions (powder)
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Peptide Sequence
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Ac-D-2Nal-pCl-D-Phe-D-3Pal-S-K(nic)-D-K(nic)-L-K(iPr)-P-D-Ala-NH₂
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Pharmacological Action & Clinical Applications
Mechanism of Action
Main Clinical Uses
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Oncology Research: Potential application in the treatment of -dependent diseases such as prostate cancer, by reducing levels through inhibiting LH and FSH release.
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Reproductive Medicine Research: Used to study the regulation of the reproductive endocrine axis, and as a research tool for developing new GnRH antagonist drugs, similar to Cetrorelix and Ganirelix but with distinct pharmacokinetic properties.
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Animal Model Research: Widely used in animal experiments (such as male rats and cynomolgus monkeys) to induce long-term inhibition of gonadal function, with dose-dependent effects on LH, levels and reproductive organ weight.
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Pharmaceutical R&D: Serves as a key tool for researching the GnRH receptor pathway and developing new drugs for hormone-related diseases.
Contraindications & Adverse Reactions
Export Compliance & Trade Information
Regulatory Attribute
HS Code & Declaration Elements
Export Documentation Requirements
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Drug Export Sales Certificate (valid for 3 years), issued by the provincial drug regulatory authority of China.
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Import License or official certification of the importing country (if required), especially complying with FDA regulations for the US market, CEP requirements for the EU market, and EAR requirements for US exports.
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Relevant qualifications: GMP Certificate, Production Approval Number, Sales Contract, etc.
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Test Reports: COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), peptide sequence verification report, purity test report (HPLC/MS).
Logistics & Packaging
Quality Assurance & After-Sales Service
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Strict Quality Control: Each batch of products undergoes HPLC, MS and peptide sequence verification tests to ensure purity, stability and structural accuracy; endotoxin testing is available upon request.
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Customized Service: We can provide customized packaging and specifications according to customer needs, including small-volume research-grade products (≥99% purity) and large-volume medical-grade products.
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After-Sales Support: Provide professional technical guidance (including reconstitution and storage instructions), timely solve logistics and customs clearance problems, and ensure smooth trade; provide relevant regulatory compliance guidance for specific markets (such as ECCN confirmation for US exports).
Note
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