جودة GMP factory supply high purity Bremelanotide PT-141  peptide  CAS 189691-06-3 PT141  powder for research مصنع
جودة GMP factory supply high purity Bremelanotide PT-141  peptide  CAS 189691-06-3 PT141  powder for research مصنع
جودة GMP factory supply high purity Bremelanotide PT-141  peptide  CAS 189691-06-3 PT141  powder for research مصنع
جودة GMP factory supply high purity Bremelanotide PT-141  peptide  CAS 189691-06-3 PT141  powder for research مصنع

ملخص المنتج

Bremelanotide PT-141 (CAS 189691-06-3) Product Details Bremelanotide PT-141, with CAS Number 189691-06-3, is a synthetic cyclic heptapeptide and a non-selective melanocortin receptor agonist, also known as Bremelanotide Acetate. It is structurally modified from α-melanocyte stimulating hormone (α...

GMP factory supply high purity Bremelanotide PT-141 peptide CAS 189691-06-3 PT141 powder for research

الخصائص الأساسية

مكان المنشأ: ووهان
الاسم التجاري: Bovita
الشهادة: DMF
رقم الموديل: بفر19

تداول العقارات

الحد الأدنى لكمية الطلب: 1 جرام
سعر: 220USD
التعبئة والتغليف القياسية: زجاجة PVC أو كيس رقائق الألومنيوم
موعد التسليم: 3-7 أيام
شروط الدفع: خطاب الاعتماد، D/A، D/P، T/T، ويسترن يونيون
القدرة على العرض: 5 كجم/شهر
تفاصيل المنتج
إبراز:

GMP Bremelanotide PT-141 peptide powder,high purity PT-141 research powder,Bremelanotide PT-141 peptide with warranty

,

high purity PT-141 research powder

,

Bremelanotide PT-141 peptide with warranty

Appearence: مسحوق
Specification: 1 جرام/5 جرام/الحقيبة
Stocks: نعم
Storage Temp: 2-8 درجة مئوية
Test Method: HPLC HNMR
Color: أبيض
Casnumber: يختلف حسب الببتيد
Puritylevel: الصف الصيدلاني
Einecs: 189691-06-3
Lead Time: 3-5 أيام عمل بعد الدفع
Product Type: الببتيد المخصص
Packagingmaterial: زجاجة PVC أو كيس رقائق الألومنيوم
Type: جي إل بي-2
وصف المنتج
مواصفات مفصلة وخصائص

Bremelanotide PT-141 (CAS 189691-06-3) Product Details
Bremelanotide PT-141, with CAS Number 189691-06-3, is a synthetic cyclic heptapeptide and a non-selective melanocortin receptor agonist, also known as Bremelanotide Acetate. It is structurally modified from α-melanocyte stimulating hormone (α-MSH), with N-terminal acetylation, Nle substitution and side-chain lactam cyclization, which significantly enhances its metabolic stability, receptor affinity and biological activity. As a high-purity peptide hormone, it strictly complies with international pharmaceutical standards (GMP, USP, EP) and is widely used in global medical research, clinical trials and pharmaceutical R&D, especially in the fields of dysfunction treatment, melanocortin system research and related drug development.

Product Basic Information

Item
Details
CAS Number
189691-06-3
Product Name
Bremelanotide; PT-141; Bremelanotide Acetate; Vyleesi® (FDA-approved brand)
Chemical Formula
C₅₀H₆₈N₁₄O₁₀
Molecular Weight
Approx. 1025.18
Appearance
White to Off-White Loose Solid Powder
Purity
≥98% (HPLC); ≥99.5% available for medical grade; Single impurity ≤2%
Solubility
Slightly soluble in DMSO, Methanol and Water (ultrasonic assistance recommended); Soluble in PBS and normal saline; Homogeneous suspension in appropriate buffers
Storage Condition
Sealed, Protected from Light; Powder: -20°C for 2 years, 4°C for 1 year; Dissolved: 4°C for 1 month (bacteriostatic water), -80°C for 6 months; Avoid repeated freeze-thaw cycles and moisture exposure
Shelf Life
24 Months under Proper Storage Conditions (powder)
Peptide Sequence
Ac-Nle-c(Asp-His-D-Phe-Arg-Trp-Lys)-OH (Acetyl-Norleucine-cyclo(Aspartate-Histidine-D-Phenylalanine-Arginine-Tryptophan-Lysine)-Carboxyl)

Pharmacological Action & Clinical Applications

Mechanism of Action

Bremelanotide PT-141 acts as a non-selective agonist of melanocortin receptors (MC1R to MC5R), with particular affinity for MC4R, which plays a key role in the central nervous system's regulation of desire and response. Its cyclic structure, formed by a lactam bridge between the side chain carboxyl of Asp and the side chain amino group of Lys, locks the active conformation and enhances receptor binding affinity. The N-terminal acetylation and Nle substitution (replacing Met) prevent peptide degradation and oxidation, extending its circulating half-life to approximately 2.7 hours. By activating melanocortin receptors in the central nervous system, it regulates desire and response through endogenous pathways, without directly affecting sex hormone levels.

Main Clinical Uses

  • Dysfunction Research: FDA-approved under the brand name Vyleesi® for the treatment of hypoactive desire disorder (HSDD) in premenopausal women, helping improve desire and response. It is also being studied for potential use in male dysfunction research.
  • Melanocortin System Research: Widely used as a tool compound to study the physiological functions of the melanocortin system, including pigmentation regulation, energy homeostasis and inflammation modulation.
  • Pharmaceutical R&D: Serves as a key tool for researching melanocortin receptor pathways and developing new drugs for dysfunction, obesity and inflammatory diseases, with ongoing clinical trials evaluating its safety and efficacy in different populations.
  • Animal Model Research: Used in animal experiments to study the role of melanocortin receptors in function, pigmentation and energy metabolism, providing a basis for clinical application research.

Contraindications & Adverse Reactions

Contraindications: Prohibited for patients with hypersensitivity to any component of the product, severe cardiovascular diseases, and those with uncontrolled hypertension or hypotension.
Adverse Reactions: Common reactions may include transient hypotension, flushing, nausea, headache and injection site reactions. Rare reactions include dizziness, fatigue and mild gastrointestinal discomfort. Regular monitoring of blood pressure is recommended during use, especially for patients with cardiovascular disease history. It is not approved for postmenopausal women or men as of March 2026.

Export Compliance & Trade Information

Regulatory Attribute

Bremelanotide PT-141 is classified as a peptide hormone drug in China, subject to the administration of Drug Import and Export License (Regulatory Code: L). It complies with GMP, USP, EP and other international pharmaceutical standards. It is FDA-approved (brand name Vyleesi®) for HSDD in premenopausal women, but not approved in the EU, UK, Canada or Australia as of March 2026. It is not a DEA-controlled substance, but requires a prescription for clinical use.

HS Code & Declaration Elements

Recommended HS Code: 2937190090 (Other peptide hormones; subject to the latest customs code of the importing country); For finished dosage forms, refer to HS Code 3004 (Medicaments for therapeutic or prophylactic uses). Note that ECCN (Export Control Classification Number) is distinct from HS Code and should be confirmed based on local regulations for US exports.
Declaration Elements: CAS Number, Product Name, Purity, Usage (Medical/Research), Composition, Brand, Peptide Sequence, Structural Modification Information (N-terminal acetylation, cyclization), etc.

Logistics & Packaging

Packaging: Aluminum foil bag or glass vial, labeled with "Drug, Protect from Light, Keep Dry", peptide sequence and structural modification information; sealed packaging to prevent moisture, contamination and peptide degradation. Vacuum-packed options are available upon request. Labeling should comply with FDA requirements for prescription drugs when exporting to the US market.
Transportation: Ambient temperature shipping is acceptable for short-distance transportation (stable at room temperature for several days during shipping and customs clearance); cold chain transportation (shipping with blue ice) is recommended for long-distance or high-temperature environments to ensure product quality. Avoid extreme temperature changes and repeated freeze-thaw cycles.

Quality Assurance & After-Sales Service

  • Strict Quality Control: Each batch of products undergoes HPLC, MS and peptide sequence verification tests to ensure purity, stability and structural accuracy; endotoxin testing (≤50EU/mg) and amino acid composition analysis (≤±10%) are available upon request. Peptide content ≥80.0% is guaranteed for research and medical grade products.
  • Customized Service: We can provide customized packaging and specifications according to customer needs, including small-volume research-grade products (≥99% purity) and large-volume medical-grade products, as well as customized solvent formulation guidance for in vivo and in vitro use.GMP factory supply high purity Bremelanotide PT-141  peptide  CAS 189691-06-3 PT141  powder for research 0
التصنيف العام
5.0
★★★★★
★★★★★
بناءً على 50 مراجعة حديثة
5 نجوم
100%
4 نجوم
0
3 نجوم
0
نجمتان
0
نجمة واحدة
0
جميع المراجعات
  • R
    Robin
    Spain Mar 13.2026
    ★★★★★
    ★★★★★
    i found it in Bovita, and bough, amazing.
  • J
    Justin
    Germany Mar 7.2026
    ★★★★★
    ★★★★★
    very good high purity, good use
  • J
    Joe
    United States Mar 6.2026
    ★★★★★
    ★★★★★
    High purity
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