GMP factory supply high purity KPV peptide CAS 67727-97-3 KPV powder for research

1. Product Overview

2. Physical & Chemical Properties

• Appearance: White to off-white crystalline powder
• Solubility: Soluble in water, methanol, and DMSO; slightly soluble in ethanol
• Melting Point: 185–190°C (decomposition)
• Loss on Drying: ≤2.0%
• Heavy Metals: ≤10 ppm
• Endotoxin: <0.5 EU/mg
• Optical Rotation: [α]²⁰/D = -25° to -30° (c=1, H₂O)

3. Key Specifications

4. Applications & Uses

• Dermatological Research: Applied in vitiligo research, as it can promote melanocyte proliferation, enhance melanin synthesis, and protect melanocytes from oxidative stress, supporting skin repigmentation studies. It is also used in anti-aging and skin repair research due to its anti-inflammatory properties.
• Biochemical & Pharmacological Research: Used to study the biological functions of α-MSH fragments, including their role in immune regulation, anti-inflammatory responses, and antioxidant defense mechanisms.
• Pharmaceutical R&D: Serves as a lead compound in the development of drugs for skin disorders, anti-inflammatory agents, and antioxidants.
• Laboratory Applications: Used in peptide structure-function studies, cell culture experiments, and enzyme activity assays related to melanocyte regulation and inflammation.

5. Mechanism of Action

• It binds to melanocortin receptors (MCRs) on melanocytes, activating signaling pathways that promote melanocyte proliferation and melanin synthesis, which is crucial for skin repigmentation in vitiligo research.
• It exhibits potent anti-inflammatory activity by inhibiting the production of pro-inflammatory cytokines and reducing oxidative stress, thereby protecting cells from inflammation-induced damage.
• It enhances the antioxidant capacity of cells, scavenging reactive oxygen species (ROS) and improving the survival microenvironment of melanocytes, which is beneficial for the treatment of oxidative stress-related skin disorders.

6. Storage & Handling

• Storage Conditions:
  • Powder: Store at -20°C for 2 years; 4°C for 1 year (sealed, protected from moisture and light).
  • Solution: Store at -80°C for long-term storage; avoid repeated freeze-thaw cycles (recommend preparing fresh solutions when needed).
• Handling Precautions: Wear lab coat, nitrile gloves, and safety goggles when handling. Avoid inhalation of dust and contact with skin/eyes. Wash hands thoroughly after use.
• Incompatibility: Avoid contact with strong oxidizing agents and acidic/basic solutions.
• Waste Disposal: Dispose of unused product and waste according to local chemical waste regulations.

7. Packaging & Shipping

• Packaging Options:
  • Small Pack: 1mg, 5mg, 10mg, 50mg, 100mg (sealed foil bag or amber glass vial, moisture-proof).
  • Bulk Pack: 1g, 5g, 10g, 50g (fiber drum with PE liner, sealed to preserve peptide activity).
• Shipping Information:
  • Non-hazardous for air and ground transport.
  • Shipping Method: Worldwide express (DHL, FedEx, UPS) for fast delivery (3-7 business days).
  • Temperature Control: Shipped with ambient temperature or ice pack; avoid extreme heat or freezing.

8. Quality Assurance & Documentation

• Certificate of Analysis (COA) with full test results
• Material Safety Data Sheet (MSDS)
• Technical Data Sheet (TDS)
• Stability data and solubility guidelines

9. Why Choose Our KPV?

• High Purity: ≥98% HPLC purity, suitable for sensitive research and assays.
• Advanced Synthesis: Manufactured using solid-phase peptide synthesis technology for high purity and structural integrity.
• Consistent Quality: Strict batch-to-batch control ensures reliable performance in research applications.
• Secure Packaging: Moisture-proof, light-resistant packaging to preserve peptide activity and stability.
• Global Service: Fast worldwide shipping, professional technical support, and custom packaging options.

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