Product Summary
GMP Standard High Purity CAS: 1420478-88-1 (S) -Benzyl 2- (8-amino-1-bromoimidazo[1, 5-a]pyrazin-3-yl) Pyrrolidine-1-Carboxylate; Acalabrutinib intermediate ; ACP196 Intermediate Product Name Acalabrutinib intermediate Intermediate CAS 55557-52-3/867165-53-5/180516-87-4/1383385-64-5/850568-25-1...
High Purity Pharmaceutical Intermediates 1420478-88-1 Acalabrutinib intermediate
Basic Properties
Trading Properties
High Purity Pharmaceutical Intermediates
,Pharmaceutical Intermediates 1420478-88-1
,Acalabrutinib intermediate High Purity
GMP Standard High Purity CAS: 1420478-88-1 (S) -Benzyl 2- (8-amino-1-bromoimidazo[1, 5-a]pyrazin-3-yl) Pyrrolidine-1-Carboxylate; Acalabrutinib intermediate ; ACP196 Intermediate
| Product Name | Acalabrutinib intermediate |
| Intermediate CAS | 55557-52-3/867165-53-5/180516-87-4/1383385-64-5/850568-25-1/1420478-88-1 |
| Appearance | A White to off-white or tan solid powder |
| Molecular formula | C21H20FN3O6S |
| Molecular Weight | 461.46 |
| Assay | 99% |
| Shelf Life | 24 months when properly stored |
| Storage | Keep in a cool, dry, dark location |
Acalabrutinib, also known as ACP-196, is an orally available Bruton tyrosine kinase (BTK) inhibitor with potential antitumor activity.When applied, ACP-196 inhibits BTK activity and blocks activation of the B cell antigen receptor (BCR) signaling pathway.This prevents B cell activation and BTK-mediated activation of downstream survival pathways.
This leads to inhibition of the growth of malignant B cells that overexpress BTK.BTK is a member of the Src associated BTK/TEC cytoplasmic tyrosine kinase family and is overexpressed in B-cell malignancies.It plays an important role in B lymphocyte development, activation, signaling, proliferation, and survival.
Supply Acalabrutinib ACP-196 Powder CAS 1420477-60-6 Acalabrutinib

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