Product Summary
GMP standard Resmetirom MGL-3196 intermediate CAS 920509-33-7 and CAS 245238-80-4 and 1581304-48-4 99% purity Product Name Resmetirom Appearance White Powder CAS NO. 920509-32-6 Storage Keep in a cool, dry, dark location Resmetirom is an oral, liver-selective thyroid hormone receptor-β (THR-β) ...
Resmetirom MGL-3196 Intermediate CAS 920509-32-6
Basic Properties
Trading Properties
Resmetirom MGL-3196 Powder
,Pharma Intermediate 920509-32-6
GMP standard Resmetirom MGL-3196 intermediate CAS 920509-33-7 and CAS 245238-80-4 and 1581304-48-4 99% purity
| Product Name | Resmetirom |
| Appearance | White Powder |
| CAS NO. | 920509-32-6 |
| Storage | Keep in a cool, dry, dark location |
Resmetirom is an oral, liver-selective thyroid hormone receptor-β (THR-β) agonist. It is a novel therapeutic agent designed to target specific metabolic pathways in the liver, offering a potential treatment for metabolic dysfunction-associated fatty liver disease (MASH), formerly known as non-alcoholic steatohepatitis (NASH).
| Items |
Standards | Results | |
Appearance |
White or off-white powder | Off-white powder | |
Identification |
By HPLC | Complies | |
Melting Point |
120ºC~130ºC | 126ºC | |
Loss on Drying |
≤1.00% | 0.21% | |
Heavy Metals |
≤ 10ppm | Complies | |
Sulfated Ash |
≤ 0.10% | 0.03% | |
Content |
17.5%~19.5% | 19.3% | |
Content |
≤ 0.1ppm | 0.09ppm | |
Lead VContent |
≤ 3.0ppm | 0.50ppm | |
Content |
≤ 0.1ppm | 0.10ppm | |
Content |
≤ 0.1ppm | 0.10ppm | |
| Microbiological Test | Coliforms:Negative | Negative | |
| Salmonella: Negative | Complies | ||
| Total plate count: ≤1000 CFU/g | Pass | ||
| Yeast&Mold: ≤50 CFU/g | Pass | ||
| Related Substances | Impurity A: ≤0.30% | 0.18% | |
| Other unknown impurity: ≤0.10% | 0.07% | ||
| Total Impurities: ≤0.50% | 0.42% | ||
Assay |
≥ 98.0% | 99.50% | |
Reference Standard |
USP Standard | ||
Conclusion |
The product complied to USP standard. | ||
Storage |
Preserve in tight,light-resistant containers in a cool place | ||
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