Product Summary
Trilostane (CAS 13647-35-3) Product Name: Trilostane CAS No.: 13647-35-3 Synonyms: WIN-24540, Modrastane, Vetoryl, (4α,5α,17β)-3,17-Dihydroxy-4,5-epoxyandrost-2-ene-2-carbonitrile Molecular Formula: C₂₀H₂₇NO₃ Molecular Weight: 329.43 g/mol Appearance: White to off-white crystalline powder 2. ...
GMP factory sale High Purity Trilostane powder cas 13647-35-3 high quality
Basic Properties
Trading Properties
Trilostane (CAS 13647-35-3)
- Product Name: Trilostane
- CAS No.: 13647-35-3
- Synonyms: WIN-24540, Modrastane, Vetoryl, (4α,5α,17β)-3,17-Dihydroxy-4,5-epoxyandrost-2-ene-2-carbonitrile
- Molecular Formula: C₂₀H₂₇NO₃
- Molecular Weight: 329.43 g/mol
- Appearance: White to off-white crystalline powder
- 2. Chemical & Physical Properties
Purity: ≥98% (HPLC), USP/EP grade available
Loss on Drying (TGA): ≤0.1%
Solubility:
Soluble in DMSO, methanol, ethanol
Slightly soluble in water
Storage Condition: 0–10°C (refrigerated), protect from light, moisture and air (air-sensitive, heat-sensitive)
Stability: 2 years under recommended storage (powder)
3. Mechanism & Bioactivity
Target: 3β-hydroxy dehydrogenase (3β-HSD), reversible competitive inhibitor
Mode of Action: Blocks cortisol, aldosterone and sex synthesis; reduces adrenal hormone levels
Key Features:
Potent oral activity
Selective for adrenal and gonadal pathways
4. Applications
Veterinary Medicine:
Brand Name: Vetoryl®
Main Use: Treatment of hyperadrenocorticism (Cushing’s syndrome) in dogs; reduces cortisol overproduction
Research & Pharma:
Postmenopausal breast cancer research (inhibits synthesis in breast tumors)
Studies on Conn’s syndrome (hyperaldosteronism) and Cushing’s syndrome
Endocrine and metabolic disorder research
5. Quality Assurance
Quality Standard: In-house standard, ≥98% (HPLC)
Certificates: COA, MSDS, HPLC, NMR available
Packaging: 1g, 5g, 10g, 50g, 100g/aluminum foil bag or customized
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