GMP factory supply aviptadil peptide powder cas 40077-57-4 purity 99%

Aviptadil Peptide Powder (CAS 40077-57-4)
High-Purity Synthetic VIP Peptide for Pulmonary & Inflammation Research

Aviptadil (also known as Vasoactive Intestinal Peptide, VIP) is a synthetic 28-amino-acid neuropeptide with the sequence His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH₂. This lyophilized powder mirrors the endogenous human VIP, a key regulator of vasodilation, immune modulation, and pulmonary homeostasis.
Key Specifications

CAS Number    40077-57-4
Molecular Formula    C₁₄₇H₂₃₈N₄₄O₄₂S
Molecular Weight    3325.80 Da
Purity    ≥98%–99% (HPLC)
Appearance    White to off-white lyophilized powder
Solubility    Soluble in water (≥1 mg/mL), 1% acetic acid, or saline
Storage    -20°C (desiccated); -80°C for long-term storage
Sequence    His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH₂

Aviptadil acts as a high-affinity agonist for VIPR1 (VPAC1) and VIPR2 (VPAC2) receptors:
Pulmonary Vasodilation: Relaxes bronchial and pulmonary vascular smooth muscle, improving lung perfusion.
Anti-Inflammatory: Inhibits pro-inflammatory cytokines (IL-6, TNF-α) and reduces alveolar macrophage activation.
Immunomodulation: Regulates T-cell and macrophage function, supporting immune homeostasis.
Anti-Proliferative: Suppresses vascular smooth muscle cell proliferation and platelet aggregation.

Applications
Respiratory Research: Critical for studying ARDS, asthma, COPD, pulmonary fibrosis, and pulmonary arterial hypertension (PAH).
Inflammation & Immunology: Investigations into cytokine regulation, neuroinflammation, and immune cell signaling.
Neuroscience: Research on neuroprotection, neurotransmitter modulation, and neurodegenerative diseases.
Pharmaceutical Development: Preclinical candidate for COVID-19-related respiratory failure and inflammatory lung disorders.

Quality Assurance
Manufactured under GMP-compliant facilities with strict QC protocols.
Validated by HPLC, Mass Spectrometry (MS), and NMR for identity and purity.
Supplied with Certificate of Analysis (COA) and Safety Data Sheet (SDS).

Why Choose Our Aviptadil?
Ultra-High Purity: ≥98% HPLC grade ensures reproducible preclinical results.
Bioactivity Guaranteed: Full receptor agonist activity verified in functional assays.
Custom Packaging: Available in 1mg, 5mg, 10mg, and bulk quantities.
Global Shipping: Fast, cold-chain delivery to research labs and biotechs worldwide.
Order Information
Product Name: Aviptadil Peptide Powder
CAS: 40077-57-4
Purity: ≥98% (HPLC)
Form: Lyophilized Powder