Product Summary
Glatiramer Acetate (CAS 147245-92-9) Product Name: Glatiramer Acetate Synonyms: Copolymer 1, Copaxone, Glatiramer CAS No.: 147245-92-9 Molecular Formula: C₂₅H₄₅N₅O₁₃ Molecular Weight: 623.65 g/mol Purity: ≥98% (HPLC) 1. Product Description Glatiramer Acetate is a synthetic polypeptide acetate salt ...
GMP factory sale High Purity Glatiramer peptide powder CAS 147245-92-9 Glatiramer peptide with WC
Basic Properties
Trading Properties
GMP high purity Glatiramer peptide powder
,Glatiramer peptide powder with WC
,CAS 147245-92-9 peptide powder
Glatiramer Acetate (CAS 147245-92-9)
1. Product Description
- Appearance: White to off-white amorphous powder
- Solubility: Slightly soluble in water & methanol
-
- Powder: -20°C for 3 years / 4°C for 2 years
- Solution: -80°C for 6 months / -20°C for 1 monthStorage:
- Shipping: Ambient or blue ice; avoid freezing & strong light
| Item | Standard |
|---|---|
| Assay (HPLC) | ≥98.0% |
| Appearance | White to off-white powder |
| Loss on Drying | ≤13.0% |
| Amino Acid Ratio | Glu:Ala:Tyr:Lys ≈ 0.141:0.427:0.095:0.338COPAXONE® |
| Heavy Metals | ≤10 ppm |
| Endotoxin | ＜0.5 EU/mg |
| Melting Point | ＞239°C (dec.) |
3. Applications & Uses
✅ Pharmaceutical (API)
- Relapsing forms of multiple sclerosis (MS):
- Clinically Isolated Syndrome (CIS)
- Relapsing-Remitting MS (RRMS)
- Active Secondary Progressive MS
- Reduces relapse frequency; used for patients intolerant to interferon-β.
✅ Research & Development
- Immunology & neurobiology studies
- Experimental Autoimmune Encephalomyelitis (EAE) models
- Neuroprotective & BDNF-modulation research
4. Mechanism of Action
- MHC competition: Blocks MBP binding to MHC-II, preventing T-cell activation.
- Immune deviation: Induces Th2 anti-inflammatory cytokines (IL-4, IL-10).
- Bystander suppression: Suppressor cells migrate to CNS, reducing local inflammation.
- Neuroprotection: Promotes oligodendrocyte & neuronal precursor proliferation.
5. Safety & Handling
- GHS Classification: Not a hazardous substance
- Personal Protection: Lab coat, gloves, goggles
- Hygiene: Wash hands after handling; avoid dust inhalation
- Incompatibility: Strong oxidizing agents
- Disposal: Follow local regulations for chemical waste
6. Packaging & Shipping
- Small Pack: 1g, 5g, 10g, 50g, 100g (sealed foil bag)
- Bulk: 1kg, 5kg, 10kg, 25kg (fiber drum with PE liner)
- Shipping:
- Non-hazardous: Worldwide express (DHL, FedEx, UPS)
- Temperature: Ambient or blue ice; do not freezeCOPAXONE®
7. Quality & Documentation
- QC: Full COA, HPLC, ¹H-NMR, MS, IR
- Support: MSDS, stability data, TDS, regulatory support
- Production: cGMP-compliant facility; strict impurity control
8. Why Choose Our Glatiramer Acetate?
- High Purity: ≥98% HPLC — ideal for API/R&D
- Consistent Quality: Verified amino acid ratio & MW distribution
- Stable Supply: Large-scale manufacturing & strict QC
- Global Shipping: Fast, secure, temperature-controlled logistics
- Expert Support: Custom packaging & technical documents
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J98% purity , nice
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Ei like the price, cheap
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MVery good price, helped my business
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