Pharmaceutical Intermediates Mirogabalin White Crystalline Powder CAS 1235479-61-4

GMP standard  Mirogabalin intermediate  CAS 1235479-61-4  and CAS 1235479-59-0  and  62327-21-3  and 27784-76-5 99% purity 

Mirogabalin (CAS 1138245-13-2) is a synthetic small-molecule drug classified as a selective αδ-1 and αδ-2 calcium channel ligand, primarily developed for treating neuro  pain. It belongs to the same pharmacological class as but exhibits higher selectivity for αδ subunits, which may improve efficacy and reduce side effects.
In its pure form (often as the besylate salt for clinical use), it appears as a white to off-white crystalline powder with a molecular formula  (for the besylate salt) and a molecular weight of 394.48 g/mol. It has good solubility in water and moderate solubility in ethanol, enabling formulation into oral tablets—ideal for once-daily administration, which enhances patient adherence.
Commercially, it meets strict pharmaceutical standards with typical purity ≥99% (analyzed via HPLC) and compliance with GMP guidelines. It is stable under recommended storage (20–25°C, protected from light and moisture) and has a shelf life of 2–3 years in formulated products. As a prescription-only medication, it is approved in multiple regions for conditions like diabetic peripheral neuropathy and postherpetic neuralgia, addressing unmet needs in chronic pain management.