GMP factory supply high purity Lemairamin and xanthoxylin CAS 29946-61-0 WGX-50

GMP factory supply high purity Lemairamin/xanthoxylin CAS 29946-61-0 WGX-50

Product Introduction 
Lemairamin (or WGX-50) is a natural compound extracted from chili peppers, which shows good efficacy in preventing Alzheimer's disease. Studies have found that it can inhibit Aβ-induced neuronal apoptosis, reduce calcium toxicity in neurons, and decrease the accumulation of Aβ oligomers in the cerebral cortex. Moreover, WGX-50 has been proven to improve the cognitive performance of mice. Research indicates that WGX-50 has the potential to prevent the assembly of amyloid protein molecules. In summary, WGX-50 has the potential to prevent Alzheimer's disease and may provide a new approach for the development of drugs targeting Aβ oligomers. Additionally, WGX-50 exhibits significant anti-inflammatory activity, making it a promising candidate drug for the treatment of inflammatory diseases. It has been found that WGX-50 has a significant effect on the skin, such as reducing wrinkles and improving skin elasticity. Besides the natural compounds extracted from the plant chili peppers, there are currently more synthetic compounds available for various applications and more suitable for the market. 

2. Characteristics 
(1) High purity: Through natural extraction and refining production processes, the piperine can be obtained in a highly pure form. High purity implies better bioavailability and fewer adverse reactions. 
(2) Safety: It has a high level of safety. 
(3) Stability: The piperine has excellent stability. It can maintain its activity and efficacy under various environmental and storage conditions. 

3. Application 
Huajixin is an amide compound extracted from the bark of the pepper tree. Currently, it is used as a dietary supplement. Additionally, it acts as an agonist of the α7 nicotinic acetylcholine receptor (α7nAChR), which can reduce neuroinflammation in Alzheimer's disease and is completely synthetic. WGX-50 demonstrated encouraging results in preclinical studies, including inhibiting Aβ-induced neuronal apoptosis, reducing neuronal calcium toxicity, reducing the accumulation of Aβ oligomers in the cerebral cortex, and improving the cognitive performance of mice.