Productoverzicht
Epirubicine HCL- CAS 56390-09-1 Artikel 1 Detail Productnaam Epirubicine HCL Synoniemen 4′-Epidoxorubicine HCl, Epidoxorubicine HCl, epi-Doxorubicine HCl CAS-nummer 56390-09-1 Moleculaire formule C27H29NO11·HCl Moleculair gewicht 579.98 MDL-nummer MFCD00941448 EINECS 260-145-2 Uiterlijk Oranje tot ...
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Epirubicine HCL- CAS 56390-09-1
| Artikel 1 | Detail |
|---|---|
| Productnaam | Epirubicine HCL |
| Synoniemen | 4′-Epidoxorubicine HCl, Epidoxorubicine HCl, epi-Doxorubicine HCl |
| CAS-nummer | 56390-09-1 |
| Moleculaire formule | C27H29NO11·HCl |
| Moleculair gewicht | 579.98 |
| MDL-nummer | MFCD00941448 |
| EINECS | 260-145-2 |
| Uiterlijk | Oranje tot dieprood kristallijn poeder |
| Zuiverheid | ≥98% (HPLC); ≥99% (HPLC); GMP-kwaliteit ≥98% |
| Oplosbaarheid | Water: 100 mg/ml (25°C); DMSO: 100 mg/ml; Methanol: oplosbaar; Ethanol: licht oplosbaar; Onoplosbaar in chloroform/ |
| Smeltepunt | 185 °C (dec.) |
| Bewaarplaats | -20°C (langdurig); 2°8°C (kortdurend), droog, afgesloten, beschermd tegen licht |
| Mechanisme | DNA-intercalator, topoisomerase II-remmer; veroorzaakt DNA-strengbrekingen, G2/M-arrest, apoptose |
| Biologische activiteit | Antitumor, cytotoxisch, antimitoxisch; lagere cardiotoxiciteit dan doxorubicine |
| Toepassingen | Borstkanker, lymfoom, eierstokkanker, longkanker, ADC-last, oncologieonderzoek |
| Graad | Onderzoeksgraad / hoge zuiverheid / GMP |
| Verpakking | 10 mg, 50 mg, 100 mg, 500 mg, 1 g, 5 g, 10 g |
| Gevaarsklasse | Cytotoxisch, carcinogeen, teratogeen, irriterend |
| VN-nummer | VN 2811 |
| SDS/COA | Op aanvraag beschikbaar |
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