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Atosiban CAS 90779-69-4, Atosiban research grade, oxytocin receptor antagonist, preterm labor research tool, Atosiban lyophilized powder, Atosiban purity ≥98% HPLC, Atosiban acetate salt, Atosiban mechanism of action, reproductive biology research peptide, tocolytic agent reference standard Product ...
GMP factory sell Atosiban cas 90779-69-4 with WC Atosiban peptide powder
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GMP Atosiban peptide powder
,WC Atosiban peptide powder
,Atosiban cas 90779-69-4
Atosiban CAS 90779-69-4, Atosiban research grade, oxytocin receptor antagonist, preterm labor research tool, Atosiban lyophilized powder, Atosiban purity ≥98% HPLC, Atosiban acetate salt, Atosiban mechanism of action, reproductive biology research peptide, tocolytic agent reference standard
Purity: ≥98.0% (RP-HPLC); Premium Grade ≥99.0%
Appearance: White to off-white sterile-filtered lyophilized powder
Solubility: Soluble in water (≤100 mg/mL); Soluble in DMSO (≥132.5 mg/mL, sonication recommended)
Storage: Long-term: -20°C (sealed, desiccated); Short-term: Room temperature for up to 3 weeks; Reconstituted: 4°C for 2–7 days (avoid repeated freeze-thaw cycles)
Grade: Research Grade / Pharmaceutical Reference Standard (For laboratory use only; not for clinical use)
- High Purity & Consistency: Manufactured via solid-phase peptide synthesis (SPPS) with rigorous RP-HPLC purification; batch-to-batch consistency validated by COA, MS, and amino acid analysis.
- Dual Receptor Antagonism: Potently blocks OTR and V1aR, inhibiting oxytocin-induced uterine contractions and prostaglandin release (PGE/PGF) from the deciduaPMC.
- Rapid Onset & Reversibility: Intravenous administration achieves rapid uterine quiescence (contractions reduced within 10 minutes) with minimal fetal/maternal cardiovascular effectsPMC.
- Stable Formulation: Lyophilized powder format preserves stability; no additional excipients, ensuring reliable reconstitution and experimental reproducibility.
- Versatile Applications: Suitable for reproductive biology, pharmacology, and drug development research; ideal for in vitro/in vivo studies of preterm labor and uterine function.
Applications
- Reproductive Biology Research: In vitro studies of myometrial contractility, oxytocin/vasopressin signaling, and preterm birth pathogenesis; in vivo animal models for evaluating tocolytic efficacy.
- Pharmacology & Drug Development: Lead compound for developing novel tocolytic agents; reference standard for OTR/V1aR binding assays and pharmacokinetic studies.
- Biomedical Research: Investigation of uterine inflammation, prostaglandin metabolism, and calcium signaling in reproductive tissues.
| Test | Specification | Method |
|---|---|---|
| Purity | ≥98.0% (Base); ≥99.0% (Premium) | RP-HPLC |
| Identity | Confirmed | Mass Spectrometry (MS), Amino Acid Analysis |
| Impurities | Residual solvents, heavy metals, endotoxins meet USP/EP standards | USP/EP Methods |
| Peptide Content | ≥95.0% | Amino Acid Analysis |
| Water Content | ≤5.0% | Karl Fischer Titration |
| Acetate Content (Salt Form) | 5.0–12.0% | HPLC |
Packaging & Shipping
- Available Sizes: 1 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg, 1 g (custom sizes available upon request)
- Packaging: Sealed amber glass vials with bromobutyl rubber stoppers; lyophilized under inert gas to prevent oxidation.
- Shipping: Shipped with ice packs (-20°C) for international orders; cold-chain logistics maintained to ensure product integrity.
Disclaimer
Why Choose Our Atosiban?
GMP-Compliant Manufacturing: Produced in cGMP facilities with strict quality control at every stage, ensuring high purity and batch consistency.
- Global Supply Chain: Reliable small-batch and bulk production to meet international research and pharmaceutical development demands.
- Comprehensive Documentation: COA, HPLC, MS, and amino acid analysis included with every order; dedicated technical team for product inquiries.
- Customization: Custom peptide modifications, labeling (fluorescent, biotin), and formulation services available to support specific research needs.
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