جودة GMP factory sell Atosiban cas 90779-69-4 with WC Atosiban peptide powder مصنع
جودة GMP factory sell Atosiban cas 90779-69-4 with WC Atosiban peptide powder مصنع
جودة GMP factory sell Atosiban cas 90779-69-4 with WC Atosiban peptide powder مصنع
جودة GMP factory sell Atosiban cas 90779-69-4 with WC Atosiban peptide powder مصنع

ملخص المنتج

Atosiban CAS 90779-69-4, Atosiban research grade, oxytocin receptor antagonist, preterm labor research tool, Atosiban lyophilized powder, Atosiban purity ≥98% HPLC, Atosiban acetate salt, Atosiban mechanism of action, reproductive biology research peptide, tocolytic agent reference standard Product ...

GMP factory sell Atosiban cas 90779-69-4 with WC Atosiban peptide powder

الخصائص الأساسية

مكان المنشأ: ووهان
الاسم التجاري: Bovita
الشهادة: WC
رقم الموديل: بفبد02

تداول العقارات

الحد الأدنى لكمية الطلب: 5 جرام
سعر: 200USD/G
التعبئة والتغليف القياسية: كيس رقائق الألومنيوم
شروط الدفع: ويسترن يونيون، تي / تي، د / ف، د / أ، خطاب الاعتماد
القدرة على العرض: 10 كجم/شهر
تفاصيل المنتج
إبراز:

GMP Atosiban peptide powder,WC Atosiban peptide powder,Atosiban cas 90779-69-4

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WC Atosiban peptide powder

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Atosiban cas 90779-69-4

Name: أتوسيبان
CAS: 90779-69-4
Color: أبيض
Appearance: مسحوق
Stocks: متاح
Delivery Time: 3-5 أيام
وصف المنتج
مواصفات مفصلة وخصائص

Atosiban CAS 90779-69-4, Atosiban research grade, oxytocin receptor antagonist, preterm labor research tool, Atosiban lyophilized powder, Atosiban purity ≥98% HPLC, Atosiban acetate salt, Atosiban mechanism of action, reproductive biology research peptide, tocolytic agent reference standard

Product Name: Atosiban
CAS Number: 90779-69-4
Synonyms: RW22164, RWJ22164, Tractocile®, Antocin®
Molecular Formula: C₄₃H₆₇N₁₁O₁₂S₂ (Base); C₄₅H₇₁N₁₁O₁₄S₂ (Acetate Salt)
Molecular Weight: 994.19 g/mol (Base); 1054.20 g/mol (Acetate Salt)
Purity: ≥98.0% (RP-HPLC); Premium Grade ≥99.0%
Appearance: White to off-white sterile-filtered lyophilized powder
Solubility: Soluble in water (≤100 mg/mL); Soluble in DMSO (≥132.5 mg/mL, sonication recommended)
Storage: Long-term: -20°C (sealed, desiccated); Short-term: Room temperature for up to 3 weeks; Reconstituted: 4°C for 2–7 days (avoid repeated freeze-thaw cycles)
Grade: Research Grade / Pharmaceutical Reference Standard (For laboratory use only; not for clinical use)
Atosiban is a synthetic nonapeptide analog of oxytocin and a potent, selective competitive antagonist of both oxytocin receptors (OTR) and vasopressin V1a receptors (V1aR)PMC. Developed by Ferring Pharmaceuticals, it is widely recognized as a first-line tocolytic agent for delaying preterm labor in clinical settings, with well-characterized safety and efficacy profiles. As a research tool, it enables precise investigation of oxytocin/vasopressin signaling pathways, uterine contractility, and preterm birth mechanisms.
  • High Purity & Consistency: Manufactured via solid-phase peptide synthesis (SPPS) with rigorous RP-HPLC purification; batch-to-batch consistency validated by COA, MS, and amino acid analysis.
  • Dual Receptor Antagonism: Potently blocks OTR and V1aR, inhibiting oxytocin-induced uterine contractions and prostaglandin release (PGE/PGF) from the deciduaPMC.
  • Rapid Onset & Reversibility: Intravenous administration achieves rapid uterine quiescence (contractions reduced within 10 minutes) with minimal fetal/maternal cardiovascular effectsPMC.
  • Stable Formulation: Lyophilized powder format preserves stability; no additional excipients, ensuring reliable reconstitution and experimental reproducibility.
  • Versatile Applications: Suitable for reproductive biology, pharmacology, and drug development research; ideal for in vitro/in vivo studies of preterm labor and uterine function.
Atosiban competes with oxytocin for binding to OTR (a GPCR) on myometrial cells, blocking Gαq-PLC-Ca²⁺ signaling cascadesPMC. This reduces intracellular calcium release from the sarcoplasmic reticulum and inhibits calcium influx through voltage-gated channels, suppressing uterine contractionsPMC. It also antagonizes V1aR, further reducing oxytocin-mediated prostaglandin production and uterine sensitivity to oxytocinPMC.

Applications

  • Reproductive Biology Research: In vitro studies of myometrial contractility, oxytocin/vasopressin signaling, and preterm birth pathogenesis; in vivo animal models for evaluating tocolytic efficacy.
  • Pharmacology & Drug Development: Lead compound for developing novel tocolytic agents; reference standard for OTR/V1aR binding assays and pharmacokinetic studies.
  • Biomedical Research: Investigation of uterine inflammation, prostaglandin metabolism, and calcium signaling in reproductive tissues.
Test Specification Method
Purity ≥98.0% (Base); ≥99.0% (Premium) RP-HPLC
Identity Confirmed Mass Spectrometry (MS), Amino Acid Analysis
Impurities Residual solvents, heavy metals, endotoxins meet USP/EP standards USP/EP Methods
Peptide Content ≥95.0% Amino Acid Analysis
Water Content ≤5.0% Karl Fischer Titration
Acetate Content (Salt Form) 5.0–12.0% HPLC

Packaging & Shipping

  • Available Sizes: 1 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg, 1 g (custom sizes available upon request)
  • Packaging: Sealed amber glass vials with bromobutyl rubber stoppers; lyophilized under inert gas to prevent oxidation.
  • Shipping: Shipped with ice packs (-20°C) for international orders; cold-chain logistics maintained to ensure product integrity.

Disclaimer

This product is intended for research and development use only and is not approved for human or veterinary clinical applications. It is not for diagnostic, therapeutic, or household use. All handling and use must comply with local laboratory safety regulations and ethical guidelines.

Why Choose Our Atosiban?

GMP-Compliant Manufacturing: Produced in cGMP facilities with strict quality control at every stage, ensuring high purity and batch consistency.

  • Global Supply Chain: Reliable small-batch and bulk production to meet international research and pharmaceutical development demands.
  • Comprehensive Documentation: COA, HPLC, MS, and amino acid analysis included with every order; dedicated technical team for product inquiries.
  • Customization: Custom peptide modifications, labeling (fluorescent, biotin), and formulation services available to support specific research needs.
For bulk orders, custom sizes, or technical support, please contact our sales team.
GMP factory sell Atosiban cas 90779-69-4 with WC Atosiban peptide powder 0
التصنيف العام
5.0
★★★★★
★★★★★
بناءً على 50 مراجعة حديثة
5 نجوم
100%
4 نجوم
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3 نجوم
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جميع المراجعات
  • M
    Max
    Germany Mar 18.2026
    ★★★★★
    ★★★★★
    I sell many in Europe, nice
  • J
    Joe
    United States Mar 6.2026
    ★★★★★
    ★★★★★
    High purity
  • A
    A*k
    Poland Mar 3.2026
    ★★★★★
    ★★★★★
    good quality, safety shipment
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